33 The Medicine That sparked A Movement
What if one of the world’s most iconic beverages wasn’t invented for taste—but for pain relief? In this episode of Twist of Fate Radio, we follow the remarkable journey of Dr. John Pemberton, a wounded Civil War veteran who set out to cure his own addiction… and accidentally created a drink that would change the world. From morphine to coca leaves, prohibition laws to soda fountains, this is the true story of how Coca-Cola began—not as a refreshment, but as a remedy. One man’s search for healing became a global brand, all because of a twist in the road. Hosted by Angela Clark. 🎧 Listen now and discover how medicine turned into magic.🌐 Explore more at TwistOfFateRadio.com

The Medicine That Sparked a Movement

How a wounded veteran’s quest for relief led to one of the world’s most iconic brands.

In the years following the American Civil War, the South was a landscape of reconstruction—physically, economically, and emotionally. Among the many veterans returning home to rebuild their lives was Dr. John Stith Pemberton, a pharmacist from Columbus, Georgia. He had survived the war, but not unscathed. A saber wound left him in chronic pain, and like many soldiers of his time, he became dependent on morphine—then a common post-surgical treatment.

Pemberton, however, was no ordinary patient. He was also a trained chemist. Driven by the need to cure his own addiction and manage his pain, he began experimenting with alternative remedies. His laboratory became a space not just of healing, but of invention.

The Coca Wine Craze

During this period, a European drink called Vin Mariani was gaining popularity. It was made by infusing Bordeaux wine with coca leaves (from which cocaine is derived). Promoted as a tonic for fatigue, depression, and even impotence, coca wine was being hailed as a miracle drink. Pemberton was intrigued.

He developed his own version called Pemberton’s French Wine Coca, a heady mix of alcohol, coca leaf extract, kola nut (a natural source of caffeine), and other botanical ingredients. The drink was advertised as a nerve tonic, promising to treat headaches, relieve exhaustion, and even curb addictions. For a time, it did exactly what Pemberton needed—manage his pain and keep his morphine use at bay.

The Law That Changed Everything

But in 1886, Atlanta’s growing temperance movement passed local legislation banning the sale of alcohol. This posed a problem for Pemberton. His product was technically medicinal—but it still contained wine, now illegal to sell.

Rather than give up, Pemberton got to work. He reformulated the drink, replacing wine with sugar syrup and maintaining the core ingredients of coca and kola. The new version was thicker, sweeter, and less intoxicating—but it still carried the promise of health benefits.

To test his creation, he brought a sample of the syrup to Jacobs’ Pharmacy in downtown Atlanta. There, a soda fountain clerk mixed it with carbonated water—an increasingly popular way of serving medicinal tonics at the time.

The result?

People loved it. Not for its healing properties, but simply for how it tasted.

From Tonic to Treat

The drink needed a name, and it was Pemberton’s bookkeeper, Frank Mason Robinson, who proposed combining its two key ingredients: coca and kola. He stylized it as Coca-Cola, believing the two “C”s would look striking in advertising. He even designed the now-iconic Spencerian script logo, which is still used today.

At first, Coca-Cola was sold as a medicine, claimed to cure everything from headaches to impotence. But sales at soda fountains quickly revealed something more powerful than the supposed cures: consumer enjoyment.

People didn’t want medicine. They wanted refreshment.

The Tragic Turn

Though Pemberton had struck upon something special, he wouldn’t live to see its success. His health was failing, and his financial situation was dire. In an effort to support his family, he began selling off portions of his Coca-Cola business rights to different investors.

One of those investors was a druggist named Asa Candler.

After Pemberton died in 1888—only two years after Coca-Cola’s debut—Candler quietly bought up remaining shares of the formula and trademark, eventually acquiring full control. Where Pemberton saw a medicine, Candler saw a movement.

He repositioned Coca-Cola not as a cure, but as a refreshing beverage, perfect for everyday enjoyment. He launched one of the most aggressive and visionary marketing campaigns of the 19th century, giving away coupons, installing branded clocks and signage, and expanding the drink’s availability beyond pharmacies and into general stores.

Under his leadership, Coca-Cola quickly became a national phenomenon.

What Was Actually in It?

Yes, early versions of Coca-Cola did contain cocaine—albeit in small amounts, as it was derived from unprocessed coca leaves. At the time, cocaine was legal and widely used in tonics and remedies. However, by the early 1900s, growing public concern about drug use prompted Coca-Cola to remove the psychoactive component.

Today, the formula remains a closely guarded secret. The coca leaves used are now de-cocainized, and the exact combination of ingredients—referred to as “Merchandise 7X”—is still known by only a few people within the company.

A Twist of Fate

John Pemberton was trying to heal himself when he invented Coca-Cola. He never intended to start a revolution in marketing, refreshment, or global branding. He never imagined his syrup would become the most recognized beverage in the world, served in over 200 countries and consumed more than 1.9 billion times a day.

One man's personal quest for relief, a prohibition law, and a chance encounter at a soda fountain all converged to create a product that would transform culture, commerce, and community.

From medicine… to magic.

From pain… to pleasure.

From a wounded veteran’s lab… to every corner of the world.

Sources:

  • Coca-Cola Company Archives: https://www.coca-colacompany.com
  • Pendergrast, Mark. For God, Country, and Coca-Cola. Basic Books, 2013.
  • National Archives: “The Real Story Behind the Coca-Cola Name”
  • Smithsonian Magazine: “How Coca-Cola Invented the Modern Marketing Machine”